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Vitamin D Benefits Breast Cancer Patients
with Joint and Muscle Pain
By: Amy Wermuth
Vitamin D Benefits Breast Cancer Patients with Joint and Muscle Pain
A new study shows that high dose vitamin D alleviates joint and muscle
pain for a lot of breast cancer patients taking estrogen lowering
medications. The study was conducted by the Washington University School
of Medicine (St. Louis).
The estrogen
lowering medications (aromatase inhibitors), are frequently given to
shrink breast tumors induced by the hormone estrogen and help thwart
cancer reappearance. These inhibitors are not as toxic chemotherapy, but
for more than 50% of breast cancer patients, the medications tend to
create relentless discomfort with muscles and joints.
Because the
inhibitors reduce cancer reappearance, doctors found disappointing
numbers of patients that stopped taking the medicine because of the
extreme discomfort experienced. To combat this issue, doctors scrambled
to find help in order to get patients to remain on them long-term.
Aromatase
inhibitors are prescribed to post menopausal breast cancer patients for
at least 5 years to help stave off reoccurrence, sometimes longer. There
is some confirmation that patients who experience the medications side
effects are less prone to see their cancer revisit and that is why there
was/is more motivation to help these patients continue taking the
inhibitors.
During a study to
create relief a professor of radiation oncology at the university that
patients on these inhibitors who suffered from joint pain and muscle
pain found some reprieve by taking high doses of vitamin D.
60 patients
experiencing the side-effects participated (many showed low vitamin D
levels). 50% of participants were randomly assigned to be given the
recommended daily dose of vitamin D (400 units) and a 50,000-unit
vitamin D capsule each 7 days. The other 50% received the daily dose of
vitamin D and a placebo each week. All participating patients received
1,000 milligrams of calcium daily during the study.
The results were
showing that many of the patients not receiving placebo were helped. The
study was supported by Astra-Zeneca, which makes the aromatase inhibitor
anastrozole (brand name Arimidex). Of course many considerations were
taken and overall the testing was a success.
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